New Possibilities Opened by Synchrotron Spectromicroscopy in Neurobiology
نویسندگان
چکیده
منابع مشابه
Photoelectron spectromicroscopy with synchrotron radiation: applications to neurobiology
We show that photoelectron spectromicroscopy with synchrotron radiation has been successfully exported from materials science to the life sciences. The transfer is well beyond mere feasibility tests. Photoelectron spectromicroscopy is in fact used for real, long-term studies in neurobiology. Specific examples are discussed, first to see in practice some applications to microchemical analysis of...
متن کاملSpatial resolution limits for synchrotron-based infrared spectromicroscopy
Detailed spatial resolution tests were performed on beamline 1.4.4 at the Advanced Light Source synchrotron facility in Berkeley, CA. The high-brightness synchrotron source is coupled at this beamline to a Thermo-Electron ContinulmXL infrared microscope. Two types of resolution tests in both the mid-IR (using a KBr beamsplitter and an MCT-A* detector) and in the near-IR (using a CaF2 beamsplitt...
متن کاملSynchrotron-Based FTIR Spectromicroscopy: Cytotoxicity and Heating Considerations.
Synchrotron radiation-based Fouriertransform infrared (SR-FTIR)spectromicroscopy is a newly emergingbioanalytical and imaging tool. This uniquetechnique provides mid-infrared (IR)spectra, hence chemical information, withhigh signal-to-noise at spatial resolutionsas fine as 3 to 10 microns. Thus it enablesresearchers to locate, identify, and trackspecific chemical events within anindividual livi...
متن کاملIndividual Human Cell Responses to Low Doses of Chemicals Studied by Synchrotron Infrared Spectromicroscopy
Vibrational spectroscopy, when combined with synchrotron radiation-based (SR) microscopy, is a powerful new analytical tool with high spatial resolution for detecting biochemical changes in individual living cells. In contrast to other microscopy methods that require fixing, drying, staining or labeling, SR-FTIR microscopy probes intact living cells providing a composite view of all of the mole...
متن کاملNondestructive Characterization by Advanced Synchrotron Light Techniques: Spectromicroscopy and Coherent Radiology
The advanced characteristics of synchrotron light has led in recent years to the development of a series of new experimental techniques to investigate chemical and physical properties on a microscopic scale. Although originally developed for materials science and biomedical research, such techniques find increasing applications in other domains - and could be quite useful for the study and cons...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Acta Physica Polonica A
سال: 1997
ISSN: 0587-4246,1898-794X
DOI: 10.12693/aphyspola.91.715